beta amyloid(1-42)，human

Sequence: DAEFRHDSGYEVHHQKLVFFAE DVGSNKGAIIGLMVGGVVIA
CAS#: 107761-42-2

Solubility: Soluble to 1mg/ml in water

Description:
Beta amyloid (1-42) is the predominant form of β-amyloid protein found in the brains of patients with Alzheimer′s disease and Down′s syndrome. Beta amyloid down-regulates bcl-2 (a key anti-apoptotic protein) and upregulates bax (cell death promoter) with evidence suggesting that it renders neurons vulnerable to age-dependent stress and neurodegeneration